| product name |
nicotinamide adenine dinucleotide phosphate NADHP |
| Specification |
99% |
| OEM/ODM |
yes |
| Package |
10G/Bag,50g/bag,100g/bag |
| Appearance |
white powder |
| MOQ |
100G |
NADPH is reduced coenzyme II, and its scientific name is reduced nicotinamide adenine dinucleotide phosphate. It is a coenzyme. N refers to nicotinamide, A refers to adenine, D refers to dinucleotide, and P refers to the phosphate group.
It plays the role of a hydrogen donor in many chemical reactions in organisms and is of great significance. It is a phosphorylated derivative of the 2'-position of the ribose ring system connected to adenine in nicotinamide adenine dinucleotide (NAD+), and participates in a variety of anabolic reactions, such as the synthesis of lipids, fatty acids and nucleotides, and can also provide energy for the fixation of carbon dioxide in dark reactions. These reactions require NADPH as a reducing agent and a donor of hydrogen anions. NADPH is the reduced form of NADP+.
| ANALYSIS |
SPECIFICATION |
RESULTS |
| Appearance |
white powder |
Complies |
| Odor |
Characteristic |
Complies |
| Tasted |
Characteristic |
Complies |
| Specification |
99% |
99.3% |
| Sieve Analysis |
100% pass 80 mesh |
Complies |
| Loss on Drying |
5% Max. |
0.0102 |
| Sulphated Ash |
5% Max. |
0.013 |
| Heavy Metal |
5ppm Max |
Complies |
| As |
2ppm Max |
Complies |
| Residual Solvents |
0.05% Max. |
Complies |
| Microbiology |
|
|
| Total Plate Count |
1000/g Max |
Complies |
| Yeast & Mold |
100/g Max |
Complies |
| E.Coli |
Negative |
Negative |
| Salmonella |
Negative |
Negative |
| Conclusion: Conform with specification. |
Compound introduction
NADPH is the product of the final electron acceptor NADP+ accepting electrons.
NAD+ and NADP+: nicotinamide adenine dinucleotide (NAD+, coenzyme I) and nicotinamide adenine dinucleotide phosphate (NADP+, coenzyme II, the oxidized form of NADPH). NAD+ and NADP+ are mainly used as coenzymes of dehydrogenases and act as hydrogen donors in enzymatic reactions.
NADPH is usually used as a reductant in biosynthesis and cannot directly enter the respiratory chain to be oxidized. Only under the action of special enzymes, the H on NADPH is transferred to NAD+ and then enters the respiratory chain in the form of NADH.
NADPH is formed in the light reaction stage of photosynthesis, enters the carbon reaction together with ATP, and participates in the fixation of CO2. The formation of NADPH is completed on the chloroplast thylakoid membrane.
PEP is the abbreviation of phosphoenolpyruvate, which is an important intermediate in glycolysis. It is produced in the light reaction stage (the main chemical formula is: NADP++ 2e-+ 2H+→ NADPH + H+), providing energy and corresponding enzymes (PEP condensing enzyme) for the carbon reaction stage. It is also a compound that fixes CO2 in plants.
Synthesis
Obtained from NAD+ accepting the γ-phosphate group of ATP under the catalysis of kinase.
In plant chloroplasts, the last step of the electron chain of the photosynthetic light reaction uses NADP+ as raw material and produces NADPH through the catalysis of ferredoxin-NADP+ reductase. The produced NADPH is then used for the assimilation of carbon dioxide in the dark reaction.
For animals, the oxidative phase of the pentose phosphate pathway is the main source of NADPH in cells, which can produce 60% of the required NADPH (also known as [H]).
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