| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
|
Still deciding? Get samples of US$ 500/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| product name | Edoxaban |
| CAS NO. | 480449-70-5 |
| Specification | 99% |
| Appearance | White powder |
| packing | 1kg/bag,25kgs/drum |
| MOQ | 1KG |
Edoxaban is a selective coagulation factor Xa inhibitor oral tablet for the prevention and treatment of deep venous thrombosis and pulmonary embolism. It is used to reduce the risk of stroke and systemic embolism in patients with non valvular atrial fibrillation (NVAF).
| Item | Specification | Test result |
| Appearance | white powder | Conforms |
| Assay | 99% | Conforms |
| Heavy metal | ≤10ppm | Conforms |
| Lead | ≤2.0ppm | Conforms |
| As | ≤2.0ppm | Conforms |
| Ca | ≤1.0ppm | Conforms |
| Me | ≤0.1ppm | Conforms |
| Total aerobic microbial count | ≤1000CFU/g | Conforms |
| Total moulds&yeast count | ≤100CFU/g | Conforms |
| Enterobacterial | ≤10MPN/g | Conforms |
| Salmonella | N.D/25g | Conforms |
| Escherichia coli | N.D/10g | Conforms |
| Staphylococcus aureus | N.D/10g | Conforms |
| Pseudomonas aeruginosa | N.D/10g | Conforms |
| Conclusion: Conform with specification. | ||
Pharmacological Action
Edoxaban works by inhibiting factor Xa, reducing the formation of thrombin, thereby preventing the blood from clotting into blood clots. This mechanism helps reduce the risk of stroke and systemic embolism.
Clinical trials have shown that edoxaban, at high doses, reduces stroke risk similarly, but with a lower incidence of major bleeding.
Clinical Application
Edoxaban is mainly used in the following situations in clinical practice:
Stroke prevention in patients with nonvalvular atrial fibrillation: Edoxaban can significantly reduce the risk of stroke in these patients.
Venous thromboembolism prevention after hip and knee replacement surgery: It can help reduce the risk of postoperative thrombosis.
Treatment and prevention of recurrence of deep vein thrombosis and pulmonary embolism: Edoxaban is excellent in the treatment and prevention of recurrence of deep vein thrombosis and pulmonary embolism.
Side Effects and Precautions
The main side effects of Edoxaban include bleeding, skin and mucous membrane bleeding, gingival bleeding, and epistaxis. Long-term use may increase the risk of bleeding, and in severe cases, adverse reactions such as thrombocytopenia and systemic bleeding may occur.
Therefore, you should strictly follow the doctor's instructions when using it, pay attention to monitoring the risk of bleeding, and adjust the treatment plan in time.
In addition, Edoxaban is approved with a boxed warning to alert healthcare professionals to dosing and safety information for specific patient populations.
){kind=link}