Customization: | Available |
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Powder: | Yes |
Customized: | Non-Customized |
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product name | Lafutidine |
CAS NO. | 118288-08-7 |
Specification | 99% |
Appearance | White powder |
packing | 1kg/bag,25kgs/drum |
MOQ | 1KG |
Lafutidine (INN) is a second generation H2 receptor antagonist having multimodal mechanism of action. It is currently marketed in Japan (Stogar) China (Lemeiting) and India (Lafaxid) It not only suppresses gastric acid secretion, but also has cytoprotective properties by the virtue of its property to induce the collagen synthesis in the gastric mucosa. It has a novel mechanism of action in addition to blocking the H2 receptors, it decreases inflammation by modulating calcitonin gene-related peptide (CGRP) and vanilloid receptors It is also found to stimulate mucin biosynthesis and promote the restitution of damaged mucosa.
Item | Specification | Test result |
Appearance | white powder | Conforms |
Assay | 99% | Conforms |
Heavy metal | ≤10ppm | Conforms |
Lead | ≤2.0ppm | Conforms |
As | ≤2.0ppm | Conforms |
Ca | ≤1.0ppm | Conforms |
Me | ≤0.1ppm | Conforms |
Total aerobic microbial count | ≤1000CFU/g | Conforms |
Total moulds&yeast count | ≤100CFU/g | Conforms |
Enterobacterial | ≤10MPN/g | Conforms |
Salmonella | N.D/25g | Conforms |
Escherichia coli | N.D/10g | Conforms |
Staphylococcus aureus | N.D/10g | Conforms |
Pseudomonas aeruginosa | N.D/10g | Conforms |
Conclusion: Conform with specification. |
Lafutidine (INN) is a second generation H2 receptor antagonist having multimodal mechanism of action. It is currently marketed in Japan (Stogar) China (Lemeiting) and India (Lafaxid) It not only suppresses gastric acid secretion, but also has cytoprotective properties by the virtue of its property to induce the collagen synthesis in the gastric mucosa. It has a novel mechanism of action in addition to blocking the H2 receptors, it decreases inflammation by modulating calcitonin gene-related peptide (CGRP) and vanilloid receptors It is also found to stimulate mucin biosynthesis and promote the restitution of damaged mucosa.