CAS 144481-98-1 Pharmaceutical Powder Landiolol Hydrochloride

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: ST-Landiolol Hydrochloride
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model No.: 144481-98-1
• Type: Chemical Medicine Raw Materal
• Volatile: Not Volatile
• CAS Registry Number: 144481-98-1
• Molecular Weight: 371.42
• Melting Point: 211ºC~216ºC
• Water Content: ≤ 0.50%
• Heavy Metals: ≤ 20ppm
• Residue on Ignition: ≤ 0.20%
• Related Substance: Total Impurities: ≤1.00%
• Particle Size: D90: ≤100µm
• Molecular Formula: C16h17n7o2s
• Reference Standard: in-House Standard
• Conclusion: The Product Complied to in-House Standard.
• Einecs: 1592732-453-0/1308068-626-2
• Transport Package: Aluminium Bag Outside and Double Plastic Bag Insid
• Specification: 99%
• Trademark: SENTIAN
• Origin: China
• Production Capacity: 50000

Product Description

Description

Product Name:Landiolol Hcl
Cas No.: 133242-30-5/144481-98-1
Einecs: 1592732-453-0/1308068-626-2
Molecular Weight: 509.59246/546.05
Formula: C25h39n3o8/C25h40cln3o8
Density:1.201
Boiling Point:727.5 °C At 760 Mmhg
Melting Point:125.4° Oc
Flash Point:393.8 °C
Appearance:White Powder
Purity: ≥98%
Packaging:According To Customer Requests
Country Of Origin:China

Application & Funtion

Rapiblyk (landiolol) is a short-term treatment for supraventricular tachycardia including atrial fibrillation and atrial flutter to reduce the ventricular rate. Rapiblyk is a short-acting beta-adrenergic blocker that helps decrease heart rate (negative chronotropic effect) with less lowering of blood pressure. It is given as an intravenous infusion in a monitored setting.

Rapiblyk mechanism of action is a selective beta-1-adrenoreceptor antagonist. By blocking  beta-1-receptors that are mainly in the heart, Rapiblyk helps to stop   being able to speed up the heart rate, which results in a slower heart rate. 

Rapiblyk FDA approval was granted on November 22, 2024, after positive results from clinical trials.

 

COA

Items	Requirements	Results
Physical & Chemical
Appearance	White powder	Conform
Odor	Characteristic	Characteristic
Particle Size	98% pass 80mesh	Complies
Loss on Drying	≤5.0%	3.65%
Ash	≤5.0%	1.96%
Solvent Residue	Meet USP standard	Complies
Pesticide Residue	Meet USP standard	Complies
Heavy Metal
Lead (Pb)	≤2.0ppm	Conform
(As)	≤1.0ppm	Conform
(Cd)	≤1.0ppm	Conform
(Hg)	≤0.1ppm	Conform
Microorganism
Total Plate Count	≤1000cfu/g	Conform
Yeasts and Molds	≤100cfu/g	Conform
Saimonella	Negative/25g	Conform
E.coli	Negative	Conform
Assay	99%	99.5%

 

Company