| Customization: | Available |
|---|---|
| Powder: | Powder |
| Customized: | Customized |
|
Still deciding? Get samples of US$ 30/gram
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| product name | NMNH |
| CAS NO. | 60-92-4 |
| Specification | 99% |
| Appearance | yellow powder |
| Package | 1KG/Bag,5kg/bag,25kg/drum |
| MOQ | 1KG |
For angina pectoris, myocardial infarction, myocarditis and cardiogenic shock. It can improve the symptoms such as palpitation, shortness of breath and chest tightness of rheumatic heart disease. Combined with chemotherapy can improve the efficacy of acute leukemia, and can also be used to induce remission of acute leukemia. In addition, it has a certain effect on chronic bronchitis, various hepatitis and psoriasis in the elderly.
Cyclic adenosine monophosphide (cAMP) is an important substance in cells involved in the regulation of substance metabolism and biological functions, and is the "second messenger" of life information transmission. In vivo, it can promote the survival of myocardial cells and enhance the ability of myocardial cells to resist injury, ischemia and hypoxia. Promote calcium ion flow into cardiomyocytes, enhance phosphorylation, promote excitation-contraction coupling, improve cardiomyocyte contractility, increase cardiac output; At the same time, it also expands peripheral blood vessels, reduces cardiac ejection impedance, reduces cardiac load before and after, increases cardiac output, and improves cardiac function. Thus, it plays the role of nourishing myocardial muscle, positive muscle strength, vasodilation, anti-platelet aggregation and anti-arrhythmia. Clinically, it is mainly used to treat cardiac insufficiency, angina and myocardial infarction. Especially to digitalis class cardiotonic drug poisoning or insensitive patients. After playing biological effects, the camp entering the cell is degraded by phosphodiesterase to 5-adenylyse-5 '-phosphate (5-AMP), which loses its activity, and then is decomposed into adenosine and phosphate. It is a protein kinase activator, a derivative of nucleotide. It is an important substance with physiological activity widely existing in human body. It is produced by adenosine triphosphate under the catalysis of adenylyl cyclase and can regulate various functional activities of cells. As the second messenger of hormones, it plays a role in regulating physiological function and material metabolism in cells, and can change the function of cell membrane, promote calcium ions in reticulocytoplasmic plasm to enter muscle fibers, thus enhancing myocardial contraction, promoting the activity of respiratory chain oxidase, improving myocardial hypoxia, alleviating the symptoms of coronary heart disease and improving electrocardiogram. In addition, it plays an important role in sugar and fat metabolism, nucleic acid and protein synthesis regulation.
| Items | Requirements | Results |
| Physical & Chemical | ||
| Appearance | White powder | Conform |
| Odor | Characteristic | Characteristic |
| Particle Size | 98% pass 80mesh | Complies |
| Loss on Drying | ≤5.0% | 3.65% |
| Ash | ≤5.0% | 1.96% |
| Solvent Residue | Meet USP standard | Complies |
| Pesticide Residue | Meet USP standard | Complies |
| Heavy Metal | ||
| Lead (Pb) | ≤2.0ppm | Conform |
| (As) | ≤1.0ppm | Conform |
| (Cd) | ≤1.0ppm | Conform |
| (Hg) | ≤0.1ppm | Conform |
| Microorganism | ||
| Total Plate Count | ≤1000cfu/g | Conform |
| Yeasts and Molds | ≤100cfu/g | Conform |
| Saimonella | Negative/25g | Conform |
| E.coli | Negative | Conform |
| Assay | 98% | 98.5% |
){kind=link}