| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| product name | Ascomycin |
| CAS NO. | 104987-12-4 |
| Specification | 99% |
| Appearance | white powder |
| Package | 1G/Bag,5g/bag,100g/bag |
| MOQ | 1G |
CAS No.: 11011-38-4
English Name: Ascomycin
English Alias: AAG; FK-520; CS-740; CGTHBA; Ascomycin; FR-900520; Nsc106410; Aids093221; IMMUNOMYCIN; Aids-093221
Molecular Formula: C43H69NO12Molecular Weight: 792.01MOLFile: 11011-38-4.mol
| Item | Specification | Result |
| Appearance | White to off-white powder | Conforms |
| Solubility | soluble in Water | Conforms |
| Identification | HPLC:The principal peak in the chromatogram obtained with the test solution is similar in retention time to the principal peak in the chromatogram obtained with reference solution. | Conforms |
| Related substances | Total impurity ≤5.0% | Conforms |
| Single impurity ≤1.0% | Conforms | |
| Water Determination | ≤1.0% | Conforms |
| Residue on lgnition | ≤0.1% | Conforms |
| Heavy Metals | ≤20ppm | Conforms |
| Microbial Limit | Total number of aerobic bacteria<100 cfu/g | Conforms |
| Total number of molds and yeast<100 cfu/g | Conforms | |
| Assay | ≥99% | 99.20% |
First, ascomycin is widely used in the field of respiratory tract infections. Respiratory tract infections are common diseases, including pneumonia, bronchitis, etc. Ascomycin has a strong inhibitory effect on a variety of bacterial infections, especially against drug-resistant strains. Therefore, ascomycin is widely used in the treatment of respiratory tract infections and has achieved remarkable results.
Secondly, ascomycin also plays an important role in the field of skin and soft tissue infections. Skin and soft tissue infections are common bacterial infections, such as cellulitis, abscesses, etc. Ascomycin has excellent tissue penetration, can quickly reach the site of infection, and has a bactericidal effect on a variety of pathogens. This makes ascomycin one of the drugs of choice for treating skin and soft tissue infections.
In addition, ascomycin also has important application value in the treatment of bone infections and joint infections. Bone infections and joint infections are serious infectious diseases that are difficult to treat. Ascomycin, through its good tissue permeability and broad-spectrum antimicrobial activity, can effectively penetrate bone and joint tissues, kill pathogenic bacteria and restore the patient's health.
In addition, ascomycin has certain applications in other infection fields, such as urinary tract infection, otitis media, etc. Ascomycin's broad-spectrum antibacterial activity and excellent pharmacokinetic properties make it one of the important drugs for the treatment of various infections.
In general, ascomycins have a wide range of applications in respiratory tract infections, skin and soft tissue infections, bone infections, and other areas of infection. It has strong antibacterial activity and adaptability, and is an important choice for doctors and patients when choosing treatment options.
The molecular formula of Ascomycin is C43H69NO12 and the molecular weight is 792.01. It has the ability to inhibit the activity of calcineurin phosphatase, thereby exerting an immunosuppressive effect. Ascomycin can prevent rejection after organ transplantation, and its IC50 value is 0.55nM, indicating that it has a significant inhibitory effect on the immune response of mouse mixed lymphocytes in in vitro experiments.
In terms of storage, Ascomycin should be stored at -20°C to ensure its stability. Its form is white crystalline solid.
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