L-Epicatechin EC SPECIFICATION |
Product name
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L-Epicatechin EC
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From
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Powder
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CAS No.
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490-46-0
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Specification
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90% |
Appearance
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pink powder
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Package
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1KG/Bag,5kg/bag,25kg/drum
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Place of Origin
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Shaan'Xi,China
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As a flavonoid substance, Epicatechin EC has many physiological activities, such as anti-oxidation, lipid-lowering and blood sugar-lowering, prevention of cardiovascular diseases, anti-inflammatory, nerve protection, and antibacterial effects. Antioxidant effect When the concentration of free radicals in the body is too high, the risk of disease will increase. The antioxidant activity of epicatechin is believed to be the ability to capture chain-carrying free radicals by providing phenolic hydrogen atoms in the A and B rings. Due to the presence of phenolic hydroxyl groups in the molecular structure of epicatechin, especially the ortho-hydroxyl groups in catechol or pyrogallol, they are easily oxidized to quinone structures, which makes it have a strong ability to capture free radicals such as reactive oxygen.
Flavonoids such as epicatechin have antioxidant, free radical scavenging, metabolism enhancing, immune regulation and anti-tumor functions. The antioxidant ability of epicatechin is believed to be the combination of the phenolic hydroxyl group in the molecule and the free radical to achieve the free radical scavenging effect, while the anti-tumor effect is to affect the cycle process of tumor cells and inhibit the cyclical growth of tumor cells. It also has many spectral antibacterial effects and is believed to have great potential for disease prevention.
As a flavonoid substance, epicatechin has many physiological activities, such as anti-oxidation, lipid-lowering and blood sugar-lowering, cardiovascular disease prevention, anti-inflammatory, nerve protection, antibacterial and other effects.
Antioxidant effect
When the concentration of free radicals in the body is too high, the risk of disease will increase. The antioxidant activity of epicatechin is believed to be the ability to capture chain-carrying free radicals by providing phenolic hydrogen atoms in the A ring and the B ring. Due to the presence of phenolic hydroxyl groups in the molecular structure of epicatechin, especially the ortho-hydroxyl groups in catechol or pyrogallol, it is easy to be oxidized to quinone structures, which makes it have a strong ability to capture free radicals such as active oxygen, and thus has the function of efficiently scavenging free radicals and lipid free radicals.
Reduce lipids and blood sugar and reduce resistance
Obese individuals often induce the occurrence of chronic diseases such as diabetes. BETTAIEB et al. found that adding 20 mg/kg body weight of epicatechin to the diet of adult rats on a high-fructose diet can reduce the damage of the signaling cascade (IR, IRK-1, Akt, ERK1/2), and reduce the upregulation of negative regulators (PKC, IKK, JNK and PTP1B) in rat adipose tissue, indicating that epicatechin alleviates resistance through its redox regulation mechanism.
Prevention of cardiovascular disease
Compared with the control group of mice on a high-cholesterol diet, the area of atherosclerotic lesions in the epicatechin-added group of mice was reduced by 27%, and the formation of plasma SAA and human-CRP induced by the diet was inhibited, and there was no effect on plasma lipids. At the same time, the anti-atherogenic effect of epicatechin is specific to severe injury types and has almost no effect on mild injuries, which indicates that epicatechin tends to alleviate severe cardiovascular lesions.





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