| Customization: | Available |
|---|---|
| CAS No.: | 928663-45-0 |
| Formula: | C15h30o5s |
|
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| product name | Chitosan Oligosaccharide |
| CAS NO. | 928663-45-0 |
| Specification | 99% |
| Appearance | White Flake |
| packing | 25kg/drum |
| MOQ | 25KG |
Chitosan oligosaccharide, also known as chitosan oligosaccharide or low-molecular-weight chitosan, is a product with a degree of polymerization between 2 and 20 obtained by degrading chitosan by special bio-enzyme technology (there are also reports of chemical degradation and microwave degradation technology). The molecular weight is ≤3200Da, and it is a low molecular weight product with good water solubility, great functional effects, and high biological activity. It has many unique functions that chitosan does not have, such as high solubility, full solubility in water, and easy absorption and utilization by organisms. Its function is 14 times that of chitosan.
Chitosan oligosaccharide is the only positively charged cationic alkaline amino oligosaccharide in nature and is animal cellulose. Chitosan oligosaccharide is a small molecule oligosaccharide with an amino group degraded from chitosan derived from shrimp and crab shells. It is a sugar chain with a degree of polymerization of 2 to 20.
| Item | Specification | Test result |
| Appearance | light brown powder | Conforms |
| Assay | 90% | Conforms |
| Heavy metal | ≤10ppm | Conforms |
| Lead | ≤2.0ppm | Conforms |
| As | ≤2.0ppm | Conforms |
| Ca | ≤1.0ppm | Conforms |
| Me | ≤0.1ppm | Conforms |
| Total aerobic microbial count | ≤1000CFU/g | Conforms |
| Total moulds&yeast count | ≤100CFU/g | Conforms |
| Enterobacterial | ≤10MPN/g | Conforms |
| Salmonella | N.D/25g | Conforms |
| Escherichia coli | N.D/10g | Conforms |
| Staphylococcus aureus | N.D/10g | Conforms |
| Pseudomonas aeruginosa | N.D/10g | Conforms |
| Conclusion: Conform with specification. | ||
Effects of Chitosan Oligosaccharides
1. Regulating intestinal microecology
Under acidic conditions, the free amino groups in chitosan oligosaccharide molecules are protonated. Protonated oligosaccharides can interact with the positively charged cell membrane of bacteria, interfere with the function of bacterial cell membranes, cause the loss of cytoplasm in bacteria, and inhibit the growth of fungi and microorganisms. Its antibacterial activity is related to the strain and concentration, and its antibacterial activity increases with increasing concentration. It has a bactericidal effect at high concentrations.
Chitosan oligosaccharides are an important type of BF. They can regulate the metabolic activities of microorganisms in the intestines of animals, improve the distribution of intestinal microbial flora, promote the growth and reproduction of bifidobacteria, thereby improving the body's immunity, lowering the pH in the intestine, inhibiting the growth of harmful intestinal bacteria, producing B vitamins, decomposing carcinogens, promoting intestinal peristalsis, and enhancing protein absorption.
2. Improving intestinal tissue morphology
Improving the production performance of animals Chitosan oligosaccharides increase the density of ileal microvilli, and also tend to become thinner and taller. The increase in microvilli height and density is conducive to increasing the absorption area of the small intestine, promoting the absorption of nutrients, and improving the utilization rate of feed.
3. Enhance immune function
The immune enhancement effect of chitosan oligosaccharides has been confirmed by many scholars. There are several explanations for its anti-infection mechanism: chitosan oligosaccharides stimulate the body, promote the increase in the number of cells in peritoneal exudate, activate macrophages, thereby increasing the generation of reactive oxygen species, and then exert an effect through oxidative bactericidal mechanisms; chitosan oligosaccharides directly activate macrophages to increase the killing activity of macrophages; chitosan oligosaccharides activate T lymphocytes to show killing activity, and sensitized T cells induce delayed hypersensitivity reactions; chitosan oligosaccharides activate T lymphocytes, thereby promoting the release of macrophage activation factor (MAF), and then activating macrophages. During the activation process, macrophages are directly activated by chitosan oligosaccharides, which can increase their sensitivity to MAF and further activate them. Therefore, it is believed that the killing activity of chitosan oligosaccharides is mainly the result of the enhanced interaction between activated T lymphocytes and macrophages.
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