Customization: | Available |
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Powder: | Yes |
Certification: | ISO 9001, FDA |
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product name | Lornoxicam |
CAS NO. | 70374-39-9 |
Specification | 99% |
Appearance | yellow powder |
packing | 1kg/bag,25kgs/drum |
MOQ | 1KG |
Lornoxicam is the chloride of tenoxicam. Its effects are similar to those of piroxicam, with analgesic, anti-inflammatory and antipyretic effects. It can selectively inhibit COX-2, and its intensity is slightly weaker than that of piroxicam. It activates the opioid neuropeptide system and exerts a central analgesic effect. This product has a weak antipyretic effect, and the required dose is 10 times the anti-inflammatory dose. Oral absorption is slow, and the peak blood concentration is reached in 24 hours. Food may reduce its absorption rate by 20% and delay its absorption rate. It is distributed throughout the body and also in the synovial fluid.
Lornoxicam can be used to treat chronic low back pain, acute sciatica, postoperative pain, acute mild to moderate pain, and joint pain and inflammation caused by osteoarthritis and rheumatoid arthritis.
Usage and Dosage:
Oral dosage form, 8-16 mg per day (8 mg per tablet, 1-2 tablets) when in pain, taken in 2-3 times. Intramuscular or intravenous injection: For short-term treatment of acute moderate pain after surgery, the recommended dose is 8 mg and the maximum daily dose is 16 mg. Some patients can add 8 mg within the first 24 hours, and deep intramuscular injection should be performed. Please follow the doctor's advice for details. Note that the intramuscular injection time of lornoxicam is at least 5 seconds and the intravenous injection time is at least 15 seconds. Patients with mild to moderate renal impairment and moderate liver impairment should consider reducing the dosage. The recommended maximum oral dose is 12 mg, taken in 2-3 times. Please follow the doctor's advice for details. Lornoxicam should not be taken for a long time or during meals.
Item | Specification | Test result |
Appearance | ywllow powder | Conforms |
Assay | 99% | Conforms |
Heavy metal | ≤10ppm | Conforms |
Lead | ≤2.0ppm | Conforms |
As | ≤2.0ppm | Conforms |
Ca | ≤1.0ppm | Conforms |
Me | ≤0.1ppm | Conforms |
Total aerobic microbial count | ≤1000CFU/g | Conforms |
Total moulds&yeast count | ≤100CFU/g | Conforms |
Enterobacterial | ≤10MPN/g | Conforms |
Salmonella | N.D/25g | Conforms |
Escherichia coli | N.D/10g | Conforms |
Staphylococcus aureus | N.D/10g | Conforms |
Pseudomonas aeruginosa | N.D/10g | Conforms |
Conclusion: Conform with specification. |
Lornoxicam can be used for acute pain after gynecological and orthopedic surgery, acute sciatica or low back pain. It can also be used for chronic low back pain, arthritis, rheumatoid arthritis and ankylosing spondylitis.
It is contraindicated in patients with acute gastrointestinal bleeding or active ulcers, moderate to severe renal impairment, severe liver impairment, severe heart failure, and pregnant and lactating women. It is contraindicated for patients under 18 years of age.
It should be used with caution in the elderly, asthmatics, patients with impaired liver and kidney function, and patients with a history of gastrointestinal bleeding or duodenal ulcers, and patients with coagulation disorders.