| Customization: | Available |
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| CAS No.: | 112163-33-4 |
| Packaging Material: | Drum |
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| product name | Lactoferrin |
| CAS NO. | 112163-33-4 |
| Specification | 92% |
| Appearance | white to pink powder |
| Package | 1KG/Bag,25Kg/drum |
| MOQ | 1Kg |
Lactoferrin (LF) is an iron-binding glycoprotein in the transferrin family. Lactoferrin exists in human milk and various secretions. It is the core immune function protein with the highest content in breast milk and very high content in colostrum. It can compete with pathogenic microorganisms for iron sources, resist the invasion of pathogenic microorganisms, and thus protect infants from immune damage.
In 1939, scientist Sorensen first isolated red protein from milk, but it was not until 1961 that iron-binding protein in human milk was extracted. Lactoferrin began to enter the public eye. With the deepening of research, scientists found that lactoferrin in breast milk and cow's milk has similar biological activity, and the amino acid sequence homology between the two reaches 69%. Based on this, with the advancement of biotechnology, global dairy companies began to develop and apply lactoferrin, known as the "gold of immune milk", to infant formula milk powder.
| Items | Standards | Results |
| Physical Analysis | ||
| Appearance | white to pink powder | Complies |
| Specification | 92% | Complies |
| Mesh Size | 100 % pass 80 mesh | Complies |
| Ash | ≤ 5.0% | 2.85% |
| Loss on Drying | ≤ 5.0% | 2.85% |
| Chemical Analysis | ||
| Heavy Metal | ≤ 10.0 mg/kg | Complies |
| Pb | ≤ 2.0 mg/kg | Complies |
| As | ≤ 1.0 mg/kg | Complies |
| Hg | ≤ 0.1 mg/kg | Complies |
| Microbiological Analysis | ||
| Total Plate Count | ≤ 1000cfu/g | Complies |
| Yeast&Mold | ≤ 100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
| Conclusion: in conformity with the enterprise standard | ||
Lactoferrin plays an important role in supporting the immune health of infants and young children. Lactoferrin is a natural protein with multiple physiological activities, which is involved in regulating immune function, antimicrobial, regulating iron absorption, promoting intestinal cell proliferation and differentiation and other pathological and physiological processes. In recent years, lactoferrin has been widely used in infants, pregnant women and the elderly. It can reduce the risk of infection in premature infants, the incidence of respiratory and gastrointestinal diseases in infants and young children, improve the anemia of infants and young children and pregnant women, increase the eradication rate of Helicobacter pylori in children and adults, and improve the immune function of the elderly.
According to the clinical trials in the 2022 "Expert Consensus on the Clinical Application of Lactoferrin in China", a lactoferrin content of 0.6g/L will effectively reduce the risk of respiratory and gastrointestinal infections in infants and young children. The content of 0.6g/L lactoferrin is equivalent to the lactoferrin content level of infant formula containing 450mg/100g lactoferrin after being mixed into milk according to the feeding table.
Applications
The wide range of biological functions of lactoferrin determines its application in food, cosmetics, animal production, medical and other fields. It can be used as an antioxidant, immunostimulant, iron supplement, drug carrier, etc. [5]; among them, it is particularly widely used in infant formula.
Food industry
As of 2021, there are a wide variety of products containing lactoferrin on the market, including yogurt, skim milk, health foods and fermented dairy products. In the late 20th century, Japanese dairy companies began to produce and sell infant formula containing lactoferrin. There are many benefits of adding lactoferrin to infant formula, including promoting iron absorption and improving intestinal flora. Clinical and animal trials have confirmed that these products containing lactoferrin are very beneficial to health. In countries and regions such as Japan and South Korea, it is popular to add lactoferrin to fermented dairy products, infant food, soy protein products, and meat products to supplement lactoferrin, enhance the body's immunity, and prevent the body from contracting viral colds, intestinal infections and other diseases.
Cosmetics
Lactoferrin is a natural substance in the human body. It has a wide range of antibacterial, anti-inflammatory, melanin-inhibiting and collagen-promoting effects. Therefore, it can be used as an effective ingredient in the development and utilization of cosmetic preparations. In the development of whitening cosmetics, the raw materials have a certain stability during the processing, and lactoferrin has extremely high stability and can be used as a raw material for processing into whitening agents. Studies have shown that the identification of the whitening function of lactoferrin on animal skin models shows that lactoferrin can reduce the formation of melanin, and the ability to inhibit melanin is directly proportional to the content of lactoferrin, which indicates that lactoferrin can be absorbed by the skin, thereby playing a whitening role. Lactoferrin can promote the synthesis of collagen in osteoblasts in the human body, make up for the loss of collagen caused by age and environmental factors, and have a whitening effect on human skin. Lactoferrin has a significant whitening effect and has broad prospects for application in cosmetics, but its molecular mechanism of action needs further study.
Animal production
When lactoferrin is added to the feed of sows, the sows can obtain a large amount of endogenous lactoferrin, which can reduce the probability of iron deficiency anemia in piglets, improve the immunity of piglets, and promote the growth of piglets. Adding lactoferrin to the daily diet of piglets can improve the intestinal microbial flora of piglets, prevent intestinal diarrhea, and enhance the intestinal absorption capacity of piglets for nutrients. Feeds with lactoferrin added can prevent the feed from being oxidized and decomposed, while enhancing the nutritional content of the feed. Lactoferrin also has the function of better maintaining its physiological functions during high-temperature processing of feed, so it can be used as a green feed additive for animal feeding.
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