| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Nicergoline |
| CAS NO. | 27848-84-6 |
| Appearance | White powder |
| Purity | 99% |
| Melting point | 136-138ºC |
| Boiling point | 594.4±50.0 °C(Predicted) |
| Density | 1.3558 |
| Application | Chemical raw materials; pharmaceutical raw materials; cerebrovascular drugs; biochemical |
| Chemical structure | |
| Usage | Nicergoline is a semi-synthetic ergot alkaloid derivative. Since its successful development in the 1960s, it has been registered and used in more than 50 countries. It has also been widely used in various diseases such as cerebrovascular disease, dementia and dizziness in China. |
| Storage | Normal Temperature |
1. Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins.
2. It has been found to increase mental agility and enhance clarity and perception.
3. It decreases vascular resistanceand increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells.
4. It has similar vasoactive properties in other areas of the body, particularly the lungs.
5. It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.
6. Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective, and behavioral disorders of older people.
Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has been found to increase mental agility and enhance clarity and perception. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs.
| Items | Requirements | Results |
| Physical & Chemical | ||
| Appearance | White powder | Conform |
| Odor | Characteristic | Characteristic |
| Particle Size | 98% pass 80mesh | Complies |
| Loss on Drying | ≤5.0% | 3.65% |
| Ash | ≤5.0% | 1.96% |
| Solvent Residue | Meet USP standard | Complies |
| Pesticide Residue | Meet USP standard | Complies |
| Heavy Metal | ||
| Lead (Pb) | ≤2.0ppm | Conform |
| (As) | ≤1.0ppm | Conform |
| (Cd) | ≤1.0ppm | Conform |
| (Hg) | ≤0.1ppm | Conform |
| Microorganism | ||
| Total Plate Count | ≤1000cfu/g | Conform |
| Yeasts and Molds | ≤100cfu/g | Conform |
| Saimonella | Negative/25g | Conform |
| E.coli | Negative | Conform |
| Assay | 98% | 98.5% |
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