| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Number | Superoxide dismutase,SOD |
| Appearance | White Powder |
| Specification | 1000000IU/g |
| CAS No | 9054-89-1 |
| Sample | Availiable |
| Test Method | HPLC UV |
| MOQ | 1KG |
| Storage | Cool Dry Place |
High quality superoxide dismutase cosmetic Superoxide dismutase powder
Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into either ordinary molecular oxygen (O2) or hydrogen per oxide (H2 O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen per oxide is also damaging, but less so, and is degraded by other enzymes such as catalase.
Activity
Superoxide dismutase has powerful antinflammatory activity. For example, SOD is a highly effective experimental treatment of chronic
inflammation in colitis. Treatment with SOD decreases reactive oxygen species generation and oxidative stress and, thus, inhibits endothelial
activation and indicate that modulation of factors that govern adhesion molecule expression and leukocyte-endothelial interactions. Therefore,
such antioxidants may be important new therapies for the treatment of inflammatory bowel disease.
Cosmetic uses
Superoxide dismutase may reduce free radical damage to skin-for example, to reduce fibrosis following radiation for breast cancer. Studies
of this kind must be regarded as tentative, however, as there were not adequate controls in the study including a lack of randomization,
double-blinding, or placebo. Superoxide dismutase is known to reverse fibrosis, perhaps through reversion of myofibroblasts back to
fibroblasts.
Commercial sources
Superoxide dismutase is commercially obtained from bovine liver, horseradish, cantaloupe and by fermenting certain bacteria, though it is
found in most living forms at diverse concentrations. For therapeutic purpose, SOD is usually injected locally. There is no evidence that
ingestion of unprotected SOD or SOD-rich foods can have any physiological effects: as all ingested SOD is broken down into amino acids
before being absorbed. However, ingestion of SOD bound to wheat proteins could improve its therapeutic activity, at least in theory.
|
Test Ltem |
Standard |
Result |
|
Traits |
SOD freeze-dried powder, white or light blue-green loose crystal freeze-dried powder or light yellow crystalline powder |
Light blue freeze-dried powder |
|
Activated |
(20000U/g-1000000U/g) |
1001000U/g |
|
Specific activity |
(20000U/g-1000000U/g) |
1001000U/g |
|
Protein content |
50%--95% |
95% |
|
Moisture content |
<3.5% |
3% |
|
PH |
6.5--7.5 |
6.7 |
|
Impurity content |
<3.5% |
3% |
|
Absorbance ratio |
<1.5 |
1.2 |
|
Heavy metal content |
||
|
Concentration of heavy metals |
10ppm |
5ppm |
|
Pb |
1.5mg/kg |
1.0mg/kg |
|
AS |
1.0mg/kg |
0.5mg/kg |
|
Hg |
0.3mg/kg |
0.1mg/kg |
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