Oat beta-glucan has the effect of lowering blood lipids and serum cholesterol, and has important effects on the prevention and treatment of cardiovascular and cerebrovascular diseases and diabetes. Among them, the active ingredient that plays a health-care role is the beta-glucan in oats.
| Oat Beta Glucan SPECIFICATION |
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Product name
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Oat Beta Glucan
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From
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Powder
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CAS No.
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Specification
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70% 90%
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Appearance
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off white powder
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Package
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1KG/Bag,5kg/bag,25kg/drum
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Place of Origin
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Shaan'Xi,China
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(1) Beta-glucan can reduce the absorption rate of fat and cholesterol in the small intestine, thereby reducing serum cholesterol; in addition, beta-glucan can also reduce the absorption of carbohydrates in the small intestine, thereby reducing plasma concentration and weakening the stimulation of cholesterol and lipoprotein synthesis;
(2) Beta-glucan binds to bile acid in the small intestine, increasing the excretion of bile acid and the synthesis of bile acid, thereby accelerating the conversion of cholesterol to bile acid;
(3) Beta-glucan is degraded by microbial fermentation in the colon to produce short-chain fatty acids, inhibiting the synthesis of cholesterol.
Other studies have shown that beta-glucan has a certain regulatory effect on blood glucose levels, hormone responses, and the biological effects of vitamins and minerals, and has a positive effect on the prevention of colon cancer. β-glucan is a low-calorie food that is not easily digested and absorbed by the human body. It can slow down the increase of glucose content in the blood, prevent and control obesity, diabetes and cardiovascular diseases. Because β-glucan has the property of absorbing water and swelling, it can absorb water and swell in the stomach after consumption, produce a sense of fullness, and prevent overeating. In addition, it can promote intestinal peristalsis in the intestine, has a permeation effect in the colon, prevent constipation, shorten the time for waste to pass through the intestine, and reduce the pollution of intestinal carcinogens to the intestine, achieving an anti-cancer effect. In the mouth, β-glucan cannot be decomposed by bacteria that cause tooth decay to produce acid and corrode enamel, and has an anti-caries effect.
Lowering cholesterol
As early as many years ago, scientists discovered that beta-glucan can reduce the rate of gastrointestinal absorption of fatty acids and reduce the synthesis of cholesterol in the human body. As the research on beta-glucan becomes more mature, scholars have conducted a large number of experiments at the animal and human experimental levels, confirming that beta-glucan has specific physiological functions in lowering cholesterol and low-density lipoprotein. Scientists have found that the effect of beta-glucan on cholesterol is mainly that it can significantly reduce total cholesterol (TC) and low-density lipoprotein cholesterol (LDI-TC) in plasma, while it has no significant effect on high-density lipoprotein (HDL) and triglycerides (TG). Oat glucan has a significant effect on lowering cholesterol in people with hyperlipidemia.
There are currently four hypotheses about the mechanism of oat glucan in lowering cholesterol:
1. It can bind bile acid, increase the excretion of bile acid, thereby reducing bile acid levels and plasma cholesterol concentrations.
2. It can be fermented by microorganisms in the intestine to produce short-chain fatty acids, which can inhibit the synthesis of cholesterol in the liver.
3. It can promote the decomposition of LDL-C.
4. It can form a high viscosity environment in the digestive tract, hindering the absorption of fat, cholesterol and bile acid by the digestive tract.
Lowering blood sugar
After consuming beta-glucan oatmeal food every day, the patient's blood sugar level can be reduced by about 50%. The use of oatmeal food has a significant effect on lowering blood sugar. Oat beta-glucan can reduce blood lipid content, improve blood flow performance, and accelerate the transport speed and efficiency of sugar components in the absorption and utilization process. At the same time, it has a good repair effect on liver and kidney tissue lesions complicated by diabetes, and can effectively reduce the decomposition of liver glycogen, thereby lowering blood sugar.
Enhance immunity
Oat beta-glucan has an immunomodulatory effect. Oat beta-glucan can increase the proliferation of mouse lymphocytes and enhance the ability of mice to resist bacterial invasion; it can stimulate the release of tumor necrosis factor (TNF-ALPHAhe) and interleukin-1 (InterlukinIL-1) by mouse peritoneal macrophages and the release of macrophage p338DI. After oral gavage or parenteral injection of oat beta-glucan, the number of serum immunoglobulins in mice increased significantly, indicating that oat beta-glucan has the effect of improving the immunity of mice.
Anti-cancer function
The short-chain fatty acids produced by oat beta-glucan fermentation in the intestine can reduce the activity of microbial metabolic enzymes such as glucosidase, glucuronidase and mitogen-activated protein kinase; the viscous beta-glucan can also increase the excretion of secondary bile acid in the intestine. These enzymes and secondary bile acid are the inducing factors of colon cancer, so oat beta-glucan has anti-cancer effect.
Improving the intestine
Oat beta-glucan cannot be hydrolyzed in the small intestine, but it is degraded in the large intestine and used as a substrate for bacterial fermentation. Fermentation produces short-chain fatty acids, especially butyric acid, which is beneficial to intestinal function. Oat beta-glucan can increase the number of bifidobacteria and lactobacilli in the intestines and feces of mice, while reducing the number of Escherichia coli. Therefore, oat beta-glucan also has the function of improving intestinal function and promoting the increase of beneficial intestinal bacteria.
Beauty effect
People have long known how to use oats to treat dry skin and itching. The method of use is to directly make oats into a paste and apply it on the skin. However, due to different production methods and different quality of oats, it is difficult to maintain a stable effect. With the development of science and technology, scientists have gradually discovered the main ingredients and mechanism of action of oatmeal for beauty and skin care.
Oatmeal β-glucan has excellent anti-aging effects, can smooth fine wrinkles, improve skin elasticity, and improve skin texture; it has a unique straight-chain molecular structure, which gives it good transdermal absorption performance; it promotes fibroblasts to synthesize collagen, promotes wound healing, repairs damaged skin, and gives the skin a silky, moisturized and smooth touch.
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