| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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| product name | Levofloxacin |
| CAS NO. | 100986-85-4 |
| Specification | 99% |
| Appearance | White powder |
| packing | 1kg/bag,25kgs/drum |
| MOQ | 5G |
Levofloxacin tablets, indications: This product is suitable for the following mild and moderate infections caused by sensitive bacteria:
1. Respiratory system infections: acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia;
2. Urinary system infections: acute pyelonephritis, complicated urinary tract infections, etc.;
3. Reproductive system infections: prostatitis, epididymitis, intrauterine infection, adnexitis, pelvic inflammatory disease (metronidazole can be used in combination when anaerobic infection is suspected);
4. Skin and soft tissue infections: infectious impetigo, cellulitis, lymphangiitis (adenitis), subcutaneous abscess, perianal abscess, etc.;
5. Intestinal infections: bacterial dysentery, infectious enteritis, salmonella enteritis, typhoid and paratyphoid fever, etc.;
6. Other infections: trauma, burns and postoperative wound infections, abdominal infections (use metronidazole in combination when necessary), mastitis, cholecystitis, cholangitis, bone and joint infections, and ENT infections, etc.
| Item | Specification | Test result |
| Appearance | white powder | Conforms |
| Assay | 99% | Conforms |
| Heavy metal | ≤10ppm | Conforms |
| Lead | ≤2.0ppm | Conforms |
| As | ≤2.0ppm | Conforms |
| Ca | ≤1.0ppm | Conforms |
| Me | ≤0.1ppm | Conforms |
| Total aerobic microbial count | ≤1000CFU/g | Conforms |
| Total moulds&yeast count | ≤100CFU/g | Conforms |
| Enterobacterial | ≤10MPN/g | Conforms |
| Salmonella | N.D/25g | Conforms |
| Escherichia coli | N.D/10g | Conforms |
| Staphylococcus aureus | N.D/10g | Conforms |
| Pseudomonas aeruginosa | N.D/10g | Conforms |
| Conclusion: Conform with specification. | ||
Pharmacological action
This product is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hinder the replication of bacterial DNA to achieve antibacterial effect.
This product has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, and Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae. It also has good antibacterial effect on some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococci, and Legionella, Mycoplasma, and Chlamydia, but has poor effect on anaerobic bacteria and enterococci.
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