| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
Still deciding? Get samples of US$ 55/gram
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| product name | Docetaxel |
| CAS NO. | 114977-28-5 |
| Specification | 99% |
| Appearance | White powder |
| packing | 1kg/bag,25kgs/drum |
| MOQ | 5G |
Docetaxel has the same effect as paclitaxel (PTX) and is an M-phase cycle-specific drug that promotes the polymerization of tubules into stable microtubules and inhibits their depolymerization, thereby significantly reducing the number of tubules and destroying the microtubule network structure. In vitro experiments have shown that it has cytotoxic effects on a variety of mouse and human tumor cell lines, and its anti-tumor spectrum is broader than that of PTX. And it can attenuate the effects of Bcl-2 and Bcl-xL gene expression.
| Item | Specification | Test result |
| Appearance | white powder | Conforms |
| Assay | 99% | Conforms |
| Heavy metal | ≤10ppm | Conforms |
| Lead | ≤2.0ppm | Conforms |
| As | ≤2.0ppm | Conforms |
| Ca | ≤1.0ppm | Conforms |
| Me | ≤0.1ppm | Conforms |
| Total aerobic microbial count | ≤1000CFU/g | Conforms |
| Total moulds&yeast count | ≤100CFU/g | Conforms |
| Enterobacterial | ≤10MPN/g | Conforms |
| Salmonella | N.D/25g | Conforms |
| Escherichia coli | N.D/10g | Conforms |
| Staphylococcus aureus | N.D/10g | Conforms |
| Pseudomonas aeruginosa | N.D/10g | Conforms |
| Conclusion: Conform with specification. | ||
Docetaxel has good efficacy for advanced breast cancer, ovarian cancer, and non-small cell lung cancer. It also has certain efficacy for head and neck cancer, pancreatic cancer, small cell lung cancer, gastric cancer, melanoma, and soft tissue sarcoma.
Docetaxel can only be used for intravenous infusion. All patients must take oral , such as, before receiving docetaxel treatment. Take it one day before docetaxel infusion, 16 mg per day, for at least 3 days to prevent allergic reactions and fluid retention. The recommended dose of docetaxel is 70-75 mg/m2, intravenous infusion for one hour, once every three weeks. According to the calculated amount of medicine used by the patient, use a syringe to draw the required dose, dilute it into 5% glucose injection or 0.9% sodium chloride injection, shake it gently, mix it evenly, and the final concentration does not exceed 0.74 mg/ml.
){kind=link}