Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus

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Powder: Yes
Customized: Customized
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  • Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
  • Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
  • Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
  • Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
  • Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
  • Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
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Overview

Basic Info.

Model NO.
SENTIAN-Tacrolimus
Certification
ISO 9001, Halal
Product Name
Tacrolimus
Test Method
HPLC
Storage
Cool Dry Place
MOQ
10g
Sample
1g
Transport
1kg/Bag, 25kg/Drum
Transport Package
Drum, Aluminum Foil Bag
Specification
99%
Trademark
SENTIAN
Origin
Shanxi, China
Production Capacity
50000tons/Year

Product Description

Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
Tacrolimus, also known as FK506, is a fermentation product isolated from Streptomyces. It is a macrolide drug and a powerful new immunosuppressant. It mainly inhibits the release of interleukin-2 (IL-2) and comprehensively inhibits the action of T lymphocytes. It is 100 times stronger than cyclosporine (CsA). In recent years, it has been marketed in 14 countries including Japan and the United States as a first-line drug for liver and kidney transplantation. Clinical trials have shown that it has a good effect in transplantation of heart, lung, intestine, bone marrow, etc. At the same time, FK506 also plays an active role in the treatment of autoimmune diseases such as atopic dermatitis (AD), systemic lupus erythematosus (SLE), and autoimmune eye diseases.
 
Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus

Product Parameters

Tacrolimus SPECIFICATION
Product name 
Tacrolimus 
From
Powder
CAS No.
104987-11-3
Specification
99%
Appearance
white powder
Package 
10G/Bag,50g/bag,25kg/drum
Place of Origin
Shaan'Xi,China
 
Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus
At the molecular level, tacrolimus apparently works by binding to a cellular protein (FKBP12) and accumulating in cells. The FKBP12-tacrolimus complex specifically binds to and inhibits calcineurin, which inhibits the calcium-dependent signal transduction pathway in T cells, thereby preventing the transcription of discontinuous lymphokine genes. This drug is a highly immunosuppressive drug, and its activity has been confirmed in vitro and in vivo. This drug inhibits the production of cytotoxic lymphocytes that form the main cause of transplant rejection. This drug inhibits T cell activation and T helper cell-dependent B cell proliferation. It also inhibits the production of lymphokines such as interleukin-2, interleukin-3 and gamma-interferon and the expression of interleukin-2 receptors. At the molecular level, the effect of this drug seems to be produced by binding to a cellular protein (FKBP), which also causes the compound to accumulate in the cell compartment. In vivo tests have found that this drug has shown efficacy in liver and kidney transplants.
 
Tacrolimus is the first choice immunosuppressive drug for liver, heart, kidney and bone marrow transplant patients. It can also be used for patients whose post-transplant rejection is resistant to traditional immunosuppressive regimens. The adverse reactions are similar to those of cyclosporine.
Tacrolimus 99% Fk506 API Fujimycin Prozraf CAS 104987-11-3 Tacrolimus

Side effects and precautions
The side effects of Tacrolimus include hypertension, renal impairment, diabetes, increased risk of infection, etc. Long-term use may cause serious side effects such as malignancies and opportunistic infections. Therefore, blood drug concentrations need to be closely monitored during use, and the dose should be adjusted according to clinical judgment.
In addition, Tacrolimus should be stored below -20°C and avoid repeated freezing and thawing to ensure its stability.


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FAQ

Q1. What's the MOQ?
A: MOQ is the minimum sales quantity of the product. Because each product has different prices and different packaging methods, there will be differences. Please consult the relevant professional sales manager for details.

Q2. What's the shipping time?
A: Usually the products we sell have enough stock to deliver the goods in a short

Q3.What transportation methods does our company have?
A: Our company cooperates with DHL and FedEx, as well as airlines and shipping companies. There are also some more efficient transportation methods, such as dedicated transportation lines.

Q4. Can you supply the free sample?
A: Generally, we will provide samples for customer testing to ensure that the quality of our products meets customer requirements.

Q5.Does our company support third-party testing?
A: Our company has long-term cooperation with well-known third-party testing agencies and can provide third-party testing services.

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