Cyclosporine is mainly used to prevent rejection of liver, kidney and heart transplants. It can be used together with adrenal cortex hormones and can also be used to treat some immune diseases.
Cyclosporine A SPECIFICATION |
Product name
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Cyclosporine A
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From
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Powder
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CAS No.
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79217-60-0
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Specification
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99%
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Appearance
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white powder
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Package
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1KG/Bag,5kg/bag,25kg/drum
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Place of Origin
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Shaan'Xi,China
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Cyclosporin is a potent immunosuppressant that can specifically inhibit the activity of helper T lymphocytes, but does not inhibit T lymphocytes, but promotes their proliferation. This product can also inhibit the activity of B lymphocytes. It can also block the cell growth cycle, and while significantly inhibiting host cell immunity, it also has an inhibitory effect on humoral immunity. It can inhibit the production of anti-graft antibodies in the body, and thus has an anti-rejection effect. This product does not affect the function of phagocytes and does not produce obvious bone marrow suppression.
Indications
Eye drops: used to prevent and treat immune rejection after corneal transplantation; capsules: organ transplantation, bone marrow transplantation, endogenous uveitis, psoriasis, rheumatoid arthritis, nephrotic syndrome; solution: suitable for preventing and treating rejection or graft-versus-host reaction after allogeneic organ transplantation or bone marrow transplantation; autoimmune diseases such as lupus nephritis and refractory nephrotic syndrome that have not been effectively treated with other immunosuppressants.
Cyclosporine eye drops are an immunosuppressant used primarily to treat dry eye and other inflammatory eye diseases. It reduces eye inflammation by inhibiting the activation of T cells, thereby relieving symptoms and improving the patient's quality of life.
1. Dry eye: Cyclosporine eye drops can effectively relieve dry eye symptoms caused by insufficient tear secretion. According to clinical research data, regular use of cyclosporine eye drops can significantly improve tear film stability and increase tear production, and about 60% to 70% of patients have improved symptoms within 3 to 6 months after use.
2. Blepharitis: This drug is also used to treat blepharitis, a chronic inflammation of the eyelid margin. Studies have shown that cyclosporine eye drops can reduce eyelid redness and discomfort, and about 50% of patients report a significant reduction in symptoms after using the drug.
3. Postoperative care for corneal transplantation: After corneal transplantation surgery, the patient's immune system may reject the new cornea. Cyclosporine eye drops can suppress the immune response, reduce the chance of rejection, and increase the success rate of transplantation. About 80% of patients have significantly controlled rejection after using the drug.
4. Allergic conjunctivitis: For patients with allergic conjunctivitis, cyclosporine eye drops can relieve symptoms such as itching, redness, and tearing of the eyes. Studies have shown that by inhibiting the release of inflammatory mediators, patients' symptoms are generally relieved within 2 to 4 weeks after using the drug.
Although cyclosporine eye drops have significant therapeutic effects, they also have certain side effects, such as eye irritation, burning sensation, and blurred vision. During use, you need to pay attention to observe your body's reactions and follow the doctor's instructions for reasonable medication to ensure that the treatment effect is maximized and adverse reactions are reduced.





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