| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| product name | Candesartan cilexetil |
| CAS NO. | 145040-37-5 |
| Specification | 99% |
| Appearance | white powder |
| Package | 1KG/Bag,25kg/drum |
| MOQ | 1KG |
Candesartan cilexetil is an angiotensin II antagonist, mainly used to treat hypertension.
Basic information
The chemical name of candesartan cilexetil is (±)-l-[(cyclohexyloxy)carbonyloxy]ethyl 2-ethoxy-1-[[2'-(1H-tetrazolyl-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate. Its chemical formula is C33H34N6O6, and its molecular weight is 610.66.
Candesartan cilexetil is slightly soluble in anhydrous ethanol, and almost insoluble in water.
Candesartan cilexetil is a selective angiotensin II receptor antagonist used to reduce peripheral vascular resistance. It is mainly used to treat essential hypertension and can be used alone or in combination with other antihypertensive drugs.
Main diseases treated
Candesartan cilexetil is mainly used to treat hypertension and can be used alone or in combination with other antihypertensive drugs; it can also be used for heart failure and prevention of recurrent migraine.
Applicable symptoms
Candesartan cilexetil can be used to relieve symptoms such as high blood pressure, headache, and migraine caused by hypertension.
| Items | Standards | Results |
| Physical Analysis | ||
| Description | white powder | Complies |
| Specification | 98%-101% | 99.20% |
| Mesh Size | 100 % pass 80 mesh | Complies |
| Loss on Drying | ≤ 5.0% | 0.03% |
| Chemical Analysis | ||
| Heavy Metal | ≤ 10.0 mg/kg | Complies |
| Pb | ≤ 2.0 mg/kg | Complies |
| As | ≤ 1.0 mg/kg | Complies |
| Hg | ≤ 0.1 mg/kg | Complies |
| Microbiological Analysis | ||
| Total Plate Count | ≤ 1000cfu/g | Complies |
| Yeast&Mold | ≤ 100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
| Conclusion: in conformity with the enterprise standard | ||
Candesartan cilexetil is mainly used to treat primary hypertension, and can be used alone or in combination with other antihypertensive drugs. Adults generally take it orally once a day, with a dose of 4-8 mg, which can be increased to 12 mg if necessary.
For patients with bilateral or unilateral renal artery stenosis, hyperkalemia, liver dysfunction, severe renal dysfunction or drug allergy history, it should be used with caution and the dose should be adjusted under the guidance of a doctor.
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