PRODUCT INFORMATION
Pyrroloquinoline quinone, whose English name is methoxatin, has a molecular formula of C14H6N2O8, a molecular weight of 330.206, a CAS registration number of 72909-34-3, and is a chemical intermediate.
PQQ SPECIFICATION |
Product name
|
Pyrroloquinoline Quinone PQQ |
From
|
Powder
|
CAS No.
|
72909-34-3 |
Specification
|
99%
|
Appearance
|
red powder
|
Package
|
1KG/Bag,5kg/bag,25kg/drum
|
Place of Origin
|
Shaan'Xi,China
|
PQQ is widely found in various common foods such as fruits, vegetables, grains, and beverages, including plant-derived foods and animal-derived foods. Its concentration ranges from 3.65-61.0 ng/g or ng/mL. The total content of PQQ and its derivative IPQ in human milk is 140-180 ng/ml, suggesting that it may play a very important role in the growth and development of newborn infants.
1. Super strong antioxidant capacity: PQQ has a strong ability to remove peroxides and can effectively remove HO• and O2•-, which is specifically reflected in: protecting mitochondria from oxidative damage; inhibiting lipid peroxides; protecting myocardial cells from ischemia-reperfusion damage; protecting the redox sites of oxidized NMDA receptors, thereby promoting the recovery of spinal cord injury, preventing brain ischemia and hypoxia, and avoiding severe shock in animal models; at the same time, PQQ can also protect the heart from myocardial ischemia and myocardial infarction. These protective effects are attributed to the antioxidant capacity of PQQ.
2. Liver protection: PQQ can protect the liver against alcohol and carbon tetrachloride-induced liver damage and TAA-induced liver fibrosis.
3. Neuroprotective effect: PQQ can improve neuronal damage caused by oxygen-glucose deprivation models, reduce changes in Nissl body content caused by D-galactose treatment, inhibit neuronal degeneration, weaken nerve damage caused by amyloid beta protein, and help promote the secretion of neurotrophic factors; in addition, PQQ can significantly improve the memory function of rats, and has obvious effects on memory retention and prevention of dementia.
4. Improvement of reproductive performance: People gave primiparous rats a diet deprived of PQQ. The results showed that if the female rats lacked PQQ in their diet, they would have reproductive disorders. After mating and giving birth, the newborn rats would show symptoms such as growth retardation and stunted development. In addition, the female rats would also be infertile or eat the newborn rats. If an appropriate amount of PQQ is supplemented at this time, the growth of the rats, the fertility and behavior of the female rats would be normal, and the growth of the rats would gradually return to normal. When fed with sufficient PQQ, the reproductive capacity and litter size of the female rats were significantly higher than those of the control group.
5. Growth factor-like effect: PQQ deprivation of the diet of maternal female rats would lead to growth retardation and stunted development in the newborn rats; the lack of PQQ in the diet would also lead to a large decrease in the lysine oxidase content in the rat skin, resulting in a decrease in the collagen content of the skin and damage to the cross-linking of elastin, which would be manifested as fragile and peeling skin, sparse hair, bent body, arched back, severe abdominal bleeding or even death. Therefore, PQQ is an essential nutritional factor for animal growth and development. When the mother supplements with sufficient PQQ, the weight of the young mice can be observed to increase significantly. In addition, PQQ has also been found in human breast milk, indicating that PQQ plays a very important role in the growth and development of young animals.
6. Anti-inflammatory function, enhancing immune regulation: PQQ can remove ROS and fight against inflammatory damage caused by oxidative stress. Injecting PQQ before injecting mice with carrageenan can reduce the inflammatory response of mouse paws caused by carrageenan. When PQQ is lacking in the diet, the content of interleukin 2 in mice is significantly reduced, and when PQQ is added, spleen cells have a better response to mitogen A and lipopolysaccharide. Adding PQQ to parenteral nutrition can increase the number of lymphocytes in the lymph nodes, as well as CD4+ and CD8+ cells in the lymph nodes, and can restore the integrity of lymphoid organs related to the intestine to a certain extent.
Q1. What's the MOQ?
A: MOQ is the minimum sales quantity of the product. Because each product has different prices and different packaging methods, there will be differences. Please consult the relevant professional sales manager for details.
Q2. What's the shipping time?
A: Usually the products we sell have enough stock to deliver the goods in a short
Q3.What transportation methods does our company have?
A: Our company cooperates with DHL and FedEx, as well as airlines and shipping companies. There are also some more efficient transportation methods, such as dedicated transportation lines.
Q4. Can you supply the free sample?
A: Generally, we will provide samples for customer testing to ensure that the quality of our products meets customer requirements.
Q5.Does our company support third-party testing?
A: Our company has long-term cooperation with well-known third-party testing agencies and can provide third-party testing services.