| Customization: | Available |
|---|---|
| Powder: | Yes |
| Certification: | ISO 9001, FDA |
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| product name | Gabexate Mesylate |
| CAS NO. | 56974-61-9 |
| Specification | 99% |
| Appearance | White powder |
| packing | 1kg/bag,25kgs/drum |
| MOQ | 1KG |
Gabexate mesylate is a serine protease inhibitor used primarily to treat pancreatitis and disseminated intravascular coagulation.
Biological activity and uses
Biological activity: Gabexate mesylate is a non-peptide protease inhibitor with an IC50 value of 0.19 μM for serine .
Uses: Mainly used to treat acute pancreatitis, acute attacks of chronic recurrent pancreatitis, acute pancreatitis complicated by surgery, frequent vascular thrombosis, etc..
In addition, it can also be used as a pharmaceutical intermediate
| Item | Specification | Test result |
| Appearance | white powder | Conforms |
| Assay | 99% | Conforms |
| Heavy metal | ≤10ppm | Conforms |
| Lead | ≤2.0ppm | Conforms |
| As | ≤2.0ppm | Conforms |
| Ca | ≤1.0ppm | Conforms |
| Me | ≤0.1ppm | Conforms |
| Total aerobic microbial count | ≤1000CFU/g | Conforms |
| Total moulds&yeast count | ≤100CFU/g | Conforms |
| Enterobacterial | ≤10MPN/g | Conforms |
| Salmonella | N.D/25g | Conforms |
| Escherichia coli | N.D/10g | Conforms |
| Staphylococcus aureus | N.D/10g | Conforms |
| Pseudomonas aeruginosa | N.D/10g | Conforms |
| Conclusion: Conform with specification. | ||
Gabexate mesylate is only for intravenous drip, 100 mg each time, 300 mg daily for the first 3 days of treatment, and 100 mg/day after the symptoms are relieved, with a course of 6 to 10 days. First, inject 5 mL of water for injection into the bottle containing the lyophilized powder of gabexate, and transfer it into 500 ml of 5% glucose or Ringer's solution after it is dissolved for intravenous drip. The drip speed should not be too fast, and should be controlled within 1 mg/kg/h, and should not exceed 2.5 mg/kg/h.
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