High Purity Cosmetic Grade Sleep 99% Purity CAS 73-31-4 Kg Melatonin Powder

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: ST-melatonin
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: /
• Other Names: Melatonin
• Selling Units: Single Item
• CAS No: \
• Single Gross Weight: 1.050kg
• Sample: 5-10g
• Single Package Size: 23X33X5 Cm
• Grade: Food Grade
• Supply Ability: 5000 Kilogram/Kilograms Per Month
• MOQ: 1kg
• Storage: Cool Dry Place
• Mf: C11h14n20
• Package: 1kg/Bag 25kg/Drum
• Shelf Life: 2years
• Application: Powder
• Name: Melatonin
• Transport Package: Aluminium Bag Outside and Double Plastic Bag Insid
• Specification: 99%Purity
• Trademark: sentian
• Origin: Shaan′xi, China
• Production Capacity: 5000 Kilogram/Kilograms Per Month

Product Description

Product Name: Melatonin MT

CAS:73-31-4

EINECS No.: 200-797-7

Plant Latin name: N-[2-(5-methoxy-3-indole) ethyl] acetamide, melatonin

Molecular formula:C13H16N2O2

Molecular weight: 232.278

Product specifications: 98%

Detection method: UV/HPLC

Density:1.175 g/cm³

Melting point: 116 - 118 ºC

Boiling point: 374.44 ºC

Flash point: 231.9 ºC

Refractive index: 1.580

Physical properties:  white powder

Solubility: Slightly soluble in water, easily soluble in alkaline aqueous solution

Application & Funtion

 

After melatonin is synthesized and stored in the pineal body, sympathetic nerve excitation innervates pineal cells to release melatonin. The synthesis of melatonin in mammals is controlled by a nervous system pathway that roughly originates in the paraventricular nucleus of the hypothalamus and projects directly or indirectly to the preganglionic sympathetic neurons in the first thoracic segment of the spinal cord. Then, through the projection of postganglionic sympathetic neurons in the superior cervical ganglion, nerve fibers forming pyramidal nerves reach the pineal gland to regulate melatonin synthesis. The secretion of melatonin has an obvious circadian rhythm, which is suppressed during the day and active at night. Melatonin can inhibit the hypothalamic-pituitary-gonadal axis, reduce the contents of releasing hormone, , and can directly act on the gonads to reduce the contents of androgen, estrogen and progesterone. In addition, MT has strong neuroendocrine immunomodulatory activity and scavenging free radical antioxidant ability, and is eventually metabolized in the liver, and the damage of liver cells can affect the level of MT in the body

 

Melatonin Efficacy:

(1) Improve sleep: It is the most well-known function of melatonin, which can shorten the time to fall asleep, reduce the number of awakenings during sleep, and make the quality of sleep more ideal. You can also take melatonin to adjust for jet lag.
(2) Regulation of immunity: melatonin can regulate cellular immunity and humoral immunity, and can also regulate the activity of a variety of cytokines, so that the immune capacity of the human body can be enhanced.

2, side effects: it is generally believed that a short time, small dose will not produce serious side effects. Long-term, large doses of melatonin can cause the following side effects: itchy skin, diarrhea, abdominal pain, headache, gynecomastia feminization, decreased progesterone levels, and lower body temperature. Serious cases include tachycardia, mental disorders, disorientation anxiety, seizures, autoimmune hepatitis, optic neuritis and so on.

 

 

 

 

COA

Items	Requirements	Results
Physical & Chemical
Appearance	White powder	Conform
Odor	Characteristic	Characteristic
Particle Size	98% pass 80mesh	Complies
Loss on Drying	≤5.0%	3.65%
Ash	≤5.0%	1.96%
Solvent Residue	Meet USP standard	Complies
Pesticide Residue	Meet USP standard	Complies
Heavy Metal
Lead (Pb)	≤2.0ppm	Conform
(As)	≤1.0ppm	Conform
(Cd)	≤1.0ppm	Conform
(Hg)	≤0.1ppm	Conform
Microorganism
Total Plate Count	≤1000cfu/g	Conform
Yeasts and Molds	≤100cfu/g	Conform
Saimonella	Negative/25g	Conform
E.coli	Negative	Conform
Assay	98%	98.5%

 

Company