| Customization: | Available |
|---|---|
| Function: | Lowering Blood Pressure |
| Certification: | GMP, ISO, HACCP, QS, KOSHER, NOP |
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|
Product name
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Monobenzone |
|
Latin Name
|
103-16-2 |
|
Color
|
WHRITE Powder
|
|
Specification
|
99% |
|
Formula
|
/ |
|
Solubility
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Water Soluble 100% Instant
|
|
Particle Size
|
100% pass 80 mesh
|
The topical application of monobenzone in animals increases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may causedestruction of melanocytes and permanent depigmentation.
The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes. Therefore, monobenzone is used as a topical medicine to permanently depigment normal skin surrounding vitiliginous lesions only in patients with disseminated (greater than 50 percent of body surface area) idiopathic vitiligo. Monobenzone is also being considered for the treatment of Melanoma.
(1)Monobenzone is the monobenzyl of . Monobenzone occurs as a white, almost tasteless
crystalline powder, soluble in alcohol and practically insoluble in water.
(2)Monobenzone is a compound used as a topical drug for medical depigmentation. The topical application of monobenzone in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes. thus, bringing about permanent dipigmentation in vitiligo patients.
(3)Monobenzone is the monobenzyl of . Monobenzone powder can be compounded to make a
depigmenting cream. It is used to whiten patchy skin and create and even skin tone that is pale and smooth.
(4)Monobenzone USP, is a strong depigmentation agent, used to treat the patients suffering from vitiligo.
(5)Monobenzone 20% ointment is used specifically for vitiligo
| Test Items | Test Standard |
| Appearance | Write powder |
| Identification | IR |
| Water | ≤1.0% |
| Ash | ≤5.0% |
| Particle size | 98% pass through 80 mesh |
| Lead(Pb) | ≤0.5ppm |
| As | ≤0.5ppm |
| Hg | ≤0.1ppm |
| Cd | ≤0.3ppm |
| Total Plate Count | ≤1000cfu/g |
| Yeast&Molds | ≤100cfu/g |
| E.Coli. | Negative/1.0g |
| Salmonella | Negative/1.0g |
| Staphylococcus aureus | Negative/1.0g |
| Assay (w/w; by HPLC) | ≥99.0% |
| Assay (area%; by HPLC) | ≥99.0% |
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