Rotundine 99% Dl-Tetrahydroberberine API CAS 10097-84-4 Antipyretic Analgesics Rotundine

• Customization: Available
• Certification: ISO, FDA, HACCP, Halal
• Product Name: Rotundine
• Model NO.: SENTIAN-Rotundine
• Test Method: HPLC
• Storage: Cool Dry Place
• MOQ: 1kg
• Sample: 1g
• Transport: 1kg/Bag, 25kg/Drum
• Transport Package: Drum, Aluminum Foil Bag
• Specification: 99%
• Trademark: SENTIAN
• Origin: Shanxi, China
• Production Capacity: 50000tons/Year

Product Description

Rotundine, whose chemical name is 2,3,9,10-tetramethoxy-5,8,13,13α-tetrahydro-6H-dibenzo[a,g]quinolizine, is an organic compound with the chemical formula C21H25NO4. It is mainly used as an analgesic. It is mainly used clinically to treat pain caused by gastric ulcer and duodenal ulcer, menstrual pain, uterine contraction pain after delivery, tension insomnia, spasmodic cough, etc.

 

Product Parameters

Rotundine SPECIFICATION
Product name	Rotundine
From	Powder
CAS No.	10097-84-4
Specification	99%
Appearance	white powder
Package	1KG/Bag,5kg/bag,25kg/drum
Place of Origin	Shaan'Xi,China

 

Rotundine

1. The effect is the same as that of tetrahydropalmatine, but it is stronger. Its hypnotic effect occurs 15 minutes after taking it and disappears after 2 hours. Because it also has an analgesic effect, it is particularly suitable for patients with insomnia due to pain.
2. It is used for pain in gastric ulcer and duodenal ulcer, menstrual pain, postpartum uterine contraction pain, tension insomnia, spasmodic cough, etc.

Rotundine has analgesic, sedative, hypnotic and tranquilizing effects. Its analgesic effect is weaker than but stronger than general antipyretic analgesics. It has no respiratory depressant effect at therapeutic doses and does not cause gastrointestinal smooth muscle spasm. It has a better effect on chronic persistent pain and dull visceral pain, but has a poorer effect on acute sharp pain (such as postoperative pain, traumatic pain, etc.) and advanced cancer pain. While producing analgesic effects, it can also cause sedation and hypnosis. The mechanism of action of this product has yet to be elucidated, and it may be related to inhibiting the ascending activation system of the brainstem reticular formation and blocking the function of dopamine receptors in the brain. The therapeutic dose is non-addictive.

1. Rotundine is well absorbed orally. It is mostly distributed in adipose tissue, followed by lungs, liver, and kidneys. It is mainly excreted through the kidneys. After that, the content in viscera decreases, but the content in fat increases, which is obviously related to the fat solubility of the product. Experiments with mice and rabbits show that the product easily penetrates the blood-brain barrier and enters the brain tissue, and is lower than the blood content after 2 hours.

2. Rotundine is mostly distributed in adipose tissue, followed by lungs, liver, and kidneys. It is mainly excreted through the kidneys. After that, the content in viscera decreases, but the content in fat increases, which is obviously related to the fat solubility of the product. Experiments with mice and rabbits show that the product easily penetrates the blood-brain barrier and enters the brain tissue, with a high concentration within a few minutes, but it decreases after 30 minutes and is lower than the blood content after 2 hours.

FAQ

Q1. What's the MOQ?
A: MOQ is the minimum sales quantity of the product. Because each product has different prices and different packaging methods, there will be differences. Please consult the relevant professional sales manager for details.

Q2. What's the shipping time?
A: Usually the products we sell have enough stock to deliver the goods in a short

Q3.What transportation methods does our company have?
A: Our company cooperates with DHL and FedEx, as well as airlines and shipping companies. There are also some more efficient transportation methods, such as dedicated transportation lines.

Q4. Can you supply the free sample?
A: Generally, we will provide samples for customer testing to ensure that the quality of our products meets customer requirements.

Q5.Does our company support third-party testing?
A: Our company has long-term cooperation with well-known third-party testing agencies and can provide third-party testing services.