| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| product name | Flunarizine HCl |
| CAS NO. | 30484-77-6 |
| Specification | 99% |
| Appearance | white powder |
| Package | 10G/Bag,50g/Bag |
| MOQ | 1G |
Flunarizine hydrochloride is an organic compound with the chemical formula C26H28Cl2F2N2. It is a vasodilator suitable for cerebral arteriosclerosis, cerebral thrombosis, cerebral embolism, cerebral circulatory disorders caused by hypertension, cerebral hemorrhage, cerebral circulatory disorders caused by arachnoid membranes, etc.
Basic information
Chemical formula: C26H28Cl2F2N2
Molecular weight: 477.417
CAS number: 30484-77-6
EINECS number: 250-216-6
Physical and chemical properties
Melting point: 204-210ºC
Boiling point: 511.3ºC
Flash point: 263ºC
Appearance: white crystalline powder
| Items | Requirements | Results |
| Physical & Chemical | ||
| Appearance | White powder | Conform |
| Odor | Characteristic | Characteristic |
| Particle Size | 98% pass 80mesh | Complies |
| Loss on Drying | ≤5.0% | 3.65% |
| Ash | ≤5.0% | 1.96% |
| Solvent Residue | Meet USP standard | Complies |
| Pesticide Residue | Meet USP standard | Complies |
| Heavy Metal | ||
| Lead (Pb) | ≤2.0ppm | Conform |
| (As) | ≤1.0ppm | Conform |
| (Cd) | ≤1.0ppm | Conform |
| (Hg) | ≤0.1ppm | Conform |
| Microorganism | ||
| Total Plate Count | ≤1000cfu/g | Conform |
| Yeasts and Molds | ≤100cfu/g | Conform |
| Saimonella | Negative/25g | Conform |
| E.coli | Negative | Conform |
| Assay | 98% | 98.5% |
Indications
1. Insufficient cerebral blood supply, vertebral artery ischemia, post-cerebral thrombosis, etc.
2. Tinnitus, dizziness.
3. Prevention of migraine.
4. Auxiliary treatment of epilepsy.
Pharmacological effects
This product has the following effects:
1. Relieve vasospasm, and have a lasting inhibitory effect on persistent vasospasm caused by vasoconstrictor substances, especially on the basilar artery and internal carotid artery, and its effect is 15 times stronger than that of cerebral isoflurane;
2. Vestibular inhibitory effect, which can increase the blood flow of cochlear arterioles and improve the circulation of vestibular organs;
3. Anti-epileptic effect, this product can block the pathological calcium overload of nerve cells and prevent paroxysmal depolarization and cell discharge, thereby avoiding epileptic seizures;
4. Protect the myocardium and significantly reduce ischemic myocardial damage
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