| Customization: | Available |
|---|---|
| CAS No.: | 9002-96-4 |
| Use: | Healthy |
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| product name | Vitamin E polyethylene glycol succinate TPGS |
| CAS NO. | 9002-96-4 |
| Specification | 99% |
| Appearance | White to Pale Yellow Waxy |
| packing | 1kg/bag,25kgs/drum |
| MOQ | 1KG |
Vitamin E Polyethylene Glycol Succinate is a mixture formed by the esterification of d-alpha tocopheryl acid succinate and polyethylene glycol. The ester mixture consists primarily of mono-esterified polyethylene glycol and a small amount of di-esterified polyethylene glycol. It contains NLT 25.0% of d-alpha tocopherol (C29H50O2).
| Item | Specification | Test result |
| Appearance | White to Pale Yellow Waxy | Conforms |
| Assay | 25% | Conforms |
| Heavy metal | ≤10ppm | Conforms |
| Lead | ≤2.0ppm | Conforms |
| As | ≤2.0ppm | Conforms |
| Ca | ≤1.0ppm | Conforms |
| Me | ≤0.1ppm | Conforms |
| Total aerobic microbial count | ≤1000CFU/g | Conforms |
| Total moulds&yeast count | ≤100CFU/g | Conforms |
| Enterobacterial | ≤10MPN/g | Conforms |
| Salmonella | N.D/25g | Conforms |
| Escherichia coli | N.D/10g | Conforms |
| Staphylococcus aureus | N.D/10g | Conforms |
| Pseudomonas aeruginosa | N.D/10g | Conforms |
| Conclusion: Conform with specification. | ||
Vitamin E polyethylene glycol succinate (TPGS) is a compound esterified by vitamin E succinate and polyethylene glycol, and is a water-soluble derivative of natural vitamin E. TPGS has lipophilic and hydrophilic groups, so it has good surfactant properties and water solubility, and can be dissolved in water and most polar organic solvents.
Application fields
TPGS is widely used in many fields:
Pharmaceuticals: TPGS is mainly used in the pharmaceutical industry to dissolve and formulate lipophilic and poorly soluble drugs to improve the absorption and bioavailability of drugs. It can also be used as a P-gp inhibitor to overcome the multidrug resistance (MDR) of various tumors.
Cosmetics and personal care: In personal care and cosmetics, TPGS is used as a formulation enhancer for water-soluble vitamin E and other active ingredients. It is hypoallergenic and non-irritating and is suitable for various skin care and care products.
Food and nutritional supplements: In the United States, TPGS can be used as a source of vitamin E in dietary supplements and foods. In Europe, it is also widely used in food additives.
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