| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| product name | Solifenacin Succinate |
| CAS NO. | 242478-38-2 |
| Specification | 99% |
| Appearance | white powder |
| Package | 1KG/Bag,25Kg/drum |
| MOQ | 1Kg |
Solifenacin Succinate, also known as solifenacin succinate, is a drug used to treat overactive bladder (OAB). Its chemical name is 1-azabicyclo[2.2.2]octan-8-yl-(1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate succinate
Solifenacin succinate tablets are a drug used to treat overactive bladder. Its efficacy and effects generally include reducing urinary urgency frequency, improving nocturnal urination, improving urinary incontinence, improving quality of life, and reducing drug side effects. The specific analysis is as follows:
1. Reduce urinary urgency frequency: This drug can reduce the urinary urgency caused by overactive bladder by inhibiting the contraction of bladder smooth muscle.
2. Improve nocturnal urination: Solifenacin succinate tablets can prolong the urine storage time of the bladder at night, reduce the number of nocturnal urination, and improve the situation of frequent urination.
3. Improve urinary incontinence: This drug reduces the involuntary contraction of the bladder by blocking the corresponding receptors of bladder smooth muscle, thereby reducing the occurrence of urinary incontinence.
4. Improve quality of life: This drug reduces urinary urgency and urinary incontinence, improves patients' symptoms, and can improve patients' quality of life.
5. Reduce drug side effects: Solifenacin succinate tablets can also reduce the effects of some drugs that stimulate gastrointestinal motility and reduce the adverse effects of these drugs on the gastrointestinal tract.
It is recommended to use this medicine as prescribed by a doctor. If any discomfort occurs, seek medical attention in a timely manner. After the cause of the disease is determined, symptomatic treatment should be carried out under the guidance of a professional doctor.
| Items | Standards | Results |
| Appearance | white powder | Complies |
| Specification | 99% | 99.20% |
| Loss on Drying | ≤ 5.0% | Complies |
| Heavy Metal | ≤ 10.0 mg/kg | Complies |
| Pb | ≤ 2.0 mg/kg | Complies |
| As | ≤ 1.0 mg/kg | Complies |
| Hg | ≤ 0.1 mg/kg | Complies |
| Total Plate Count | ≤ 1000cfu/g | Complies |
| Yeast&Mold | ≤ 100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
| Conclusion: in conformity with the enterprise standard | ||
Medical Uses
Solifenacin Succinate is mainly used to treat overactive bladder (OAB) and relieve symptoms such as urinary incontinence and/or frequent urination and urgency. The recommended dose is one 5 mg tablet once a day, which can be increased to two 10 mg tablets once a day if necessary. The drug is suitable for patients with mild to moderate renal dysfunction, but it should be used with caution in patients with severe renal dysfunction, and the dose should not exceed 5 mg per day.
For patients with moderate liver dysfunction, the dose should also be adjusted with caution and not exceed 5 mg per day.
Side Effects and Contraindications
Common side effects include dry mouth, constipation, and blurred vision, which are usually mild to moderate and dose-related.
Dry mouth occurred in 11% of patients treated with 5 mg once daily and 22% of patients treated with 10 mg once daily.
Contraindications include patients with urinary retention, severe gastrointestinal disease, myasthenia gravis or narrow-angle glaucoma, and patients with hypersensitivity to drug components or excipients.
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